Proteomics Group, Institute of Functional Genomics, University Regensburg 










Dr. Jörg Reinders                      Project Leader                              +49 (0) 941 943 5004


        Professional History:

        Since 04/2008          Assistant at the Institute of Functional Genomics, University Regensburg

        10/2005 - 03/2008     Assistant at the Chair of Pharmaceutical Biology, Julius-Maximilians-Universität Würzburg,     

        2003 - 2006              Continuation of doctoral thesis at the Rudolf-Virchow-Center for Experimental Biomedicine,

                                       Julius-Maximilians-Universität Würzburg, Germany

        2002 - 2003              First part of doctoral thesis at Medical Proteome-Center, Ruhr-Universität Bochum, Germany

    “Analyse des mitochondrialen Proteoms und Phosphoproteoms von Saccharomyces cerevisiae

        Educational History:

        09/2001 - 04/2002      Diploma thesis at the Medical Proteome-Center, Ruhr-Universität Bochum, Germany

                                                      “Entwicklung neuer Methoden zur Isolierung und Charakterisierung von Phosphopeptiden“

        1997 - 2002               Biochemistry study, Ruhr-Universität Bochum, Germany


        Research articles (Peer reviewed):

        Sickmann, A., Reinders, J., Wagner, Y., Joppich, C., Zahedi, R., Meyer, HE., Schonfisch, B., Perschil, I., Chacinska, A., Guiard,         B., Rehling, P., Pfanner, N., Meisinger, C. (2003)
        The proteome of Saccharomyces cerevisiae mitochondria.
        Proc Natl Acad Sci U S A. 100 (23): 13207-12.

        Reinders J., Zahedi R.P., Pfanner N., Meisinger C. and Sickmann A. (2006)
        Toward the Complete Yeast Mitochondrial Proteome: Multidimensional Separation Techniques for Mitochondrial Proteomics.
        J Proteome Res. 5(7):1543-54.

        Hahlen K., Ebbing B., Reinders J., Mergler J., Sickmann A. and Woehlke G. (
        Feedback of Kinesin-1's Neck-Linker Position on the Catalytic Site.
        J Biol Chem. 281(27):18868-77.

        Reinders J., Meyer H.E. and Sickmann A. (
        Applications of highly sensitive phosphopeptide derivatization methods without the need for organic solvents.
        Proteomics. 6(9):2647-49.

        Schönleben S., Sickmann A., Mueller M.J. and Reinders J. (2007)
          Proteome analysis of Apis mellifera royal jelly
        Anal Bioanal Chem. 389:1087-94.

        Reinders J., Wagner K., Zahedi R.P., Stojanovski D., Eyrich B., Van der Laan M., Rehling P., Sickmann A., Pfanner N.
        and Meisinger C.
          Profiling phosphoproteins of yeast mitochondria reveals a role of phosphorylation in assembly of the ATP synthase.
        Mol Cell Proteomics. 6:1896-906.

        Henning A., Reinders Y., Giritich A., Reinders J. und Warzecha H. (2008)
        Assessement of Different Expression Strategies for the Production of a Recombinant Lipoprotein Vaccine in Plants.
        The open Biotechnology Journal; 2:51-55.

        Randolt, K., Gimple, O., Geißendörfer, J., Reinders, J., Prusko, C., Mueller, M.J., Albert, S., Tautz, J., Beier, H. (2008)
        Immune-related proteins induced in the hemolymph after aseptic and septic injury differs in honey bee worker larvae and adults.
 Arch Insect Biochem Physiol. 69(4):155-67.

        Dueckershoff, K., Mueller, S., Mueller, M.J., Reinders, J.
        Impact of cyclopentenone-oxylipins on the proteome of Arabidopsis thaliana.
        Biochim. Biophys. Acta. 

         Fischer A, Baljuls A, Reinders J, Nekhoroshkova E, Sibilski C, Metz R, Albert S, Rajalingam K, Hekman M, Rapp UR. (2009)
        Regulation of RAF activity by 14-3-3 proteins: RAF kinases associate functionally with both homo- and heterodimeric forms of             14-3-3 proteins. J Biol Chem. 284(5):3183-94.

        Voss K, Stahl S, Hogan BM, Reinders J, Schleider E, Schulte-Merker S, Felbor U (2009)
        Functional analyses of human and zebrafish 18-amino acid in-frame deletion pave the way for domain mapping of the cerebral             cavernous malformation 3 protein.
Hum Mutat. 2009 Jun;30(6):1003-11. 20.

        Wingenter K, Trentmann O, Winschuh I, Hörmiller II, Heyer AG, Reinders J, Schulz A, Geiger D, Hedrich R, Neuhaus HE (2011)
        A member of the mitogen-activated protein 3-kinase family is involved in the regulation of plant vacuolar glucose uptake.
    Plant J. 2011 Dec;68(5):890-900.

        Thomas A, Stevens AP, Klein MS, Hellerbrand C, Dettmer K, Gronwald W, Oefner PJ, Reinders J (2012)
        Early changes in the liver-soluble proteome of mice fed a nonalcoholic steatohepatits inducing diet.
   Proteomics. 2012 May;12(9):1437-51.

        Sanges C, Scheuermann C, Zahedi RP, Sickmann A, Lamberti A, Migliaccio N, Baljuls A, Marra M, Zappavigna S, Reinders J,    
        Rapp U, Abbruzzese A, Caraglia M, Arcari P
        Raf kinases mediate the phosphorylation of eukaryotic translation elongation factor 1A and regulate its stability in eukaryotic cells.
        Cell Death Dis. 2012 Mar 1;3:e276.

        Escalante-Pérez M, Jaborsky M, Reinders J, Kurzai O, Hedrich R, Ache P (2012)
        Poplar Extrafloral Nectar Is Protected against Plant and Human Pathogenic Fungus.
    Mol Plant. 2012 Sep;5(5):1157-9.

        Thomas A, Klein MS, Stevens AP, Reinders Y, Hellerbrand C, Dettmer K, Gronwald W, Oefner PJ, Reinders J (2013)
        Changes in the hepatic mitochondrial and membrane proteome in mice fed a non-alcoholic steatohepatitis inducing diet.

        J Proteomics. 2013 Jan 9;80C:107-122.

        Book articles:

          Reinders J. and Sickmann A. (2007)
        Proteomics of Yeast Mitochondria. In: Mitochondria Practical Protocols.
        Methods Mol Biol. 372:543-57.

        Review articles:

        Reinders, J., Lewandrowski, U., Moebius, J., Wagner, Y. Sickmann, A. (2004)
        Challenges in mass spectrometry-based proteomics.
        Proteomics. 4 (12): 3686-703.

        Putz S., Reinders J., Reinders Y. Sickmann A. (2005)
        Mass spectrometry-based peptide quantification: applications and limitations.
        Expert Rev Proteomics. 2(3): 381-92.

        Reinders J. and Sickmann A. (2005)
        State-of-the-art in phosphoproteomics.
        Proteomics. 5(16):4052-61.

        Reinders J. and Sickmann A. (2007)
           Modificomics: Posttranslational modifications beyond protein phosphorylation and glycosylation.

        Biomol Eng. 24(2):169-77.

        Selected Talks:

          Bruker User Meeting 2004, Leipzig, "Protein-chemistry-assisted MALDI-TOF/TOF-MS"
        National University of Ireland Maynooth, 2005, "Characterization of the mitochondrial Proteome of
Saccharomyces cerevisiae"